endometriosis classification-the quest for the holy grail?

The Holy Grail and the quest for the gold standard.

I n this issue of the American Journal of Neuroradiology, Jaremko et al 1 report that apparent diffusion coefficient (ADC) values are not always reliable to discriminate medullo-blastomas from pilocytic astrocytomas (PAs according to the 2007 WHO classification of brain tumors 2 , instead of previously used juvenile pilocytic astrocytomas JPAs). This article raises a number of important issues....

Impact assessment and the quest for the Holy Grail

Conducting focus group discussions in Lake Naivasha Evaluation is seen as vital for both accountability and learning purposes. This involves understanding not only what worked but also the process of change and why and how an intervention worked. Donors, programme managers and evaluators often claim to seek not only successful outcomes, but the ‘holy grail’ of impact. This paper surveys the min...

Emphysema's Holy Grail, The Quest for Endobronchial Lung Volume Reduction

Copyright: © 2016 Maloney JD, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Citation: Maloney JD, Macke RA (2016) Emphysema's Holy Grail, The Quest for Endobronchial Lung Volume Reduction. Chron Obstr...

Pursuing the "Holy Grail".

Over the past decade, several large, randomized trials have allowed us to better define the appropriate population for primary prevention implantable cardioverterdefibrillator (ICD) placement, saving thousands of lives every year. MADIT II (Multicenter Automatic Defibrillator Implantation Trial II) and SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial) have demonstrated a survival benefit o...

Searching for the Holy Grail?

The ideal conduit for surgical revascularization: the quest for the holy grail continues.

Coronary artery bypass grafting has been an important treatment option for patients with significant obstructive and flow-limiting coronary artery disease for decades. Although there was a decline in the number of procedures performed with the introduction of and subsequent improvements in percutaneous revascularization, surgical revascularization continues to be an appropriate and effective th...